Dr. Yana Cen

Polarity of Hydrated Phosphatidylcholine Headgroups.

CoAuthors: Subramaniam R, Lynch S, Cen Y, Balaz S.

Langmuir. 2019 Jun 25;35(25):8460-8471.


Dr. Umesh Desai

 A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo withohttps://www.ncbi.nlm.nih.gov/pubmed/31244216ut enhanced risk of bleeding.

CoAuthors:  Al-Horani RA, Abdelfadiel EI, Afosah DK, Morla S, Sistla JC, Mohammed B, Martin EJ, Sakagami M, Brophy DF, Desai UR.

J Thromb Haemost. 2019 Dec;17(12):2110-2122. 


Perspective on computational simulations of glycosaminoglycans.

CoAuthors:  Nagarajan B, Sankaranarayanan NV, Desai UR.

Wiley Interdiscip Rev Comput Mol Sci. 2019 Mar-Apr;9(2). pii: e1388..


On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients.

CoAuthors: Morla S, Sankaranarayanan NV, Afosah DK, Kumar M, Kummarapurugu AB, Voynow JA, Desai UR.

J Med Chem. 2019 Jun 13;62(11):5501-5511. 


A Synthetic, Small, Sulfated Agent Is a Promising Inhibitor of Chlamydia spp. Infection in vivo.

CoAuthors: Gallegos KM, Taylor CR, Rabulinski DJ, Del Toro R, Girgis DE, Jourha D, Tiwari V, Desai UR, Ramsey KH.

Front Microbiol. 2019 Jan 16;9:3269. 


Keith Ellis

CtBP-a targetable dependency for tumor-initiating cell activity and metastasis in pancreatic adenocarcinoma.

Co-authors: Chawla AT, Chougoni KK, Joshi PJ, Cororaton AD, Memari P, Stansfield JC, Park H, Seth R, Szomju B, Sima AP, Idowu MO, Ellis KC, Grossman SR.

Oncogenesis. 2019 Oct 4;8(10):55.


A Combined Offline and Online Algorithm for Real-Time and Long-Term Classification of Sheep Behaviour: Novel Approach for Precision Livestock Farming.

CoAuthors: Vázquez-Diosdado JA, Paul V, Ellis KA, Coates D, Loomba R, Kaler J.

Sensors (Basel). 2019 Jul 20;19(14). pii: E3201. 


Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Coregulatory Activities.

CoAuthors: Dcona MM, Damle PK, Zarate-Perez F, Morris BL, Nawaz Z, Dennis MJ, Deng X, Korwar S, Singh SJ, Ellis KC, Royer WE, Bandyopadhyay D, Escalante C, Grossman SR.

Mol Pharmacol. 2019 Jul;96(1):99-108. 


Glen Kellogg

Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities.

CoAuthors: Tripathi A, Martinez E, Obaidullah AJ, Lete MG, Lönnfors M, Khan D, Soni KG, Mousley CJ, Kellogg GE, Bankaitis VA.

J Biol Chem. 2019 Dec 13;294(50):19081-19098. 


3D interaction homology: The hydropathic interaction environments of even alanine are diverse and provide novel structural insight.

CoAuthors: Ahmed MH, Catalano C, Portillo SC, Safo MK, Neel Scarsdale J, Kellogg GE.

J Struct Biol. 2019 Aug 1;207(2):183-198. 


Jiong Li

Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells. 

CoAuthors: Mingqing Wu, Lu Sheng, Maosheng Cheng, Haojie Zhang, Yizhou Jiang, Shuibin Lin, Yu Liang, Fengyu Zhu, Zhenqing Liu, Yingyin Zhang, Xiuhong Zhang, Qian Gao

Oncogene 38, 5425-5439.   


Aaron May

Animal Models of Type III Secretion System-Mediated Pathogenesis.

CoAuthors: Hotinger JA, May AE.

Pathogens. 2019 Nov 22;8(4). pii: E257.


Natural Product Type III Secretion System Inhibitors.

CoAuthors: Pendergrass HA, May AE.: 10.3390/antibiotics8040162. Review.


Martin Safo

Zein-alpha lipoic acid-loaded nanoparticles to enhance the oral bioavailability of dapoxetine: optimization and clinical pharmacokinetic evaluation.

CoAuthors: El-Say KM, Ahmed OA, Mohamed AI, Safo MK, Omar AM.

Int J Nanomedicine. 2019 Sep 12;14:7461-7473. 


Pyridoxamine Supplementation Effectively Reverses the Abnormal Phenotypes of Zebrafish Larvae With PNPO Deficiency.

CoAuthors: Chen PY, Tu HC, Schirch V, Safo MK, Fu TF.

Front Pharmacol. 2019 Sep 20;10:1086. 


Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products.

CoAuthors: Abdallah HM, Zakaria EM, El-Halawany AM, Mohamed GA, Safo MK, El-Bassossy HM.

PLoS One. 2019 Sep 6;14(9):e0222101. 


3D interaction homology: The hydropathic interaction environments of even alanine are diverse and provide novel structural insight.

CoAuthors: Ahmed MH, Catalano C, Portillo SC, Safo MK, Neel Scarsdale J, Kellogg GE.

J Struct Biol. 2019 Aug 1;207(2):183-198. doi: 10.1016/j.jsb.2019.05.007. Epub 2019 May 18.